The Clinical Problem Solvers
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Journal of
The Clinical
Problem Solvers
Spot the DiagnosisSep 1, 2026

A Patient with Liver Lesions

Renzo A. Moreno Macedo, MD

A 57-year-old woman presented to the emergency department with one week of cough and subjective fever. Chest imaging showed no pulmonary abnormalities, but multiple liver lesions were incidentally identified. She had no abdominal pain or ga...

In ReflectionMay 28, 2026

Carried Away

Alec Rezigh, MD

A reflection on caring for a young uninsured patient whose primary hyperparathyroidism went undiagnosed for years until a car accident finally forced admission. An honest reckoning with the gratitude patients extend to a healthcare system t...

Tempo and FrameApr 15, 2026

Twists of Fate

Jeffrey Shen, MD, Austin Rezigh, MD, Marcela Araujo de Oliveira Santana, MD, Alec Rezigh, MD

A young man with inflammatory bowel disease on immunosuppressive therapy presented with acute gastrointestinal symptoms and evolving systemic abnormalities. Initial evaluation favored common infectious and inflammatory etiologies; however, ...

Clinical Reasoning CornerApr 1, 2026

A Young Woman with Recurrent Lymphadenopathy and Fatigue

Jeffrey Shen, MD

A young woman with a two-year history of recurrent cervical lymphadenopathy, fatigue, and systemic symptoms underwent an extensive evaluation for infectious, malignant, and autoimmune causes, all of which were unrevealing. Despite persisten...